2016 Materials science lecture series: advanced materials - 1 December 2016
Dec 01, 2016 - 14.00 uur
Expertisecentrum voor Digitale Media
Lokaal EDM auditorium
de heer Rajesh RAMANETI
MRS/E-MRS joint student chapter, Hasselt University with IMO-IMOMEC: 2016 materials science lecture series: advanced materials.
Speaker: Prof. Dr. Lenka Zajickova - Dept. phys. electronics, Faculty of science & plasma technologies, Central European institute for technology, Masaryk University Brno, Czech Republic.
Topic: Plasma and thin films
Chaired by: Prof. Dr. Milos Nesladek, IMO-IMOMEC, Hasselt University
Thursday 1 December 2016, 14:00 -15:00
EDM auditorium, Wetenschapspark 2, Hasselt University, Campus Diepenbeek.
Plasma polymerization provides a large playground for the preparation of surfaces suitable for immobilization of biomolecules and colonization by cell because chemical, structural and functional properties of plasma polymerized thin films can be tuned accordingly. The key decision for the particular application is the selection of functional chemical group that the final plasma polymer should contain. This contribution is going to discuss deposition of plasma polymers containing amine and carboxyl groups, functional groups that are typically used in biochemical applications and that are proposed to influence positively the attachment and proliferation of cells at surfaces.
Amine-rich films were deposited in the low pressure pulsed radio frequency discharge using vapors of cyclopropylamine mixed with argon. The plasma polymers containing anhydride groups that hydrolyzed fastly at air into carboxyl groups were deposited in kHz-frequency dielectric barrier discharge at atmospheric pressure from the mixture of maleic anhydride and acetylene. Amine and carboxyl plasma polymers proved to be useful for the preparation of immunosensors based either on the principle of quartz crystal microbalance or surface plasmon resonance because in both these methods it is necessary to prepare a stable and reactive film on the gold surface. The amine films were also tested for the cultivation of human dermal fibroblasts and mouse myoblasts. It was identified that the water stability of the films is very important for successful experiments. The plasma polymers can be also prepared on electrospun polymer nanofibers which structure is suitable for tissue engineering applications.