The Charcot Foundation provides 50% more operating resources for MS research: with an eye for research with practical results, Progressive MS, and faithful to its mission: fundamental research and innovation.
Prof. Niels Hellings(BIOMED), Prof. Anitha Ethirajan (IMO-IMOMEC) and Prof. Tanja Junkers (IMO-IMOMEC) were laureats of the Charcot Fund.
While extensive research has been conducted into the disease mechanisms of MS, little is known about the exact etiology of this disease. The limited accessibility due to the presence of a protective layer, called the blood-brain barrier (BBB), is an obstacle to the study of the affected central nervous system (CNS) in the patients. This barrier acts as a neuroprotective shield by blocking foreign substances, including the imaging tracers that could help display and monitor the disease processes. In this project, functionalized tracers are being developed for research into the disease activity behind a closed BBB. If this succeeds, they will provide a better and more accurate understanding of progressive MS and enable easier evaluation of the treatments for this subpopulation of patients for which effective treatments are currently lacking.