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Research

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Details research group Immunology - Biochemistry (IMMUN)


Expertise of the research group :

Neuro-inflammatory and autoimmune disease We study the disease mechanism of multiple sclerosis and rheumatoid arthritis, two autoimmune diseases that target the central nervous system and joints respectively. We are particularly interested in the underlying immune dysfunctions (e.g. T cell regulation defects) in these diseases, and try to unravel the molecular and cellular events involved in tissue destruction and tissue repair. We are using various in vitro approaches (lymphocyte and neuronal cell cultures) and in vivo animal models (rodents) to study these research questions. We are also developing new therapeutic strategies for these diseases (e.g. T cell vaccination). In addition we use proteomics and phage display technologies to identify and test new disease markers. We are specialized in brain and cerebrospinal fluid proteomics. Molecular markers are further tested for their application in diagnosis, prognosis or theranostics. Biosensors Together with the Institute for Materials Research of our university, we are developing new biosensors to measure disease related molecules. We use conjugated polymers and CVD diamond for the development of new biolectronic devices using specific antibodies or oligonucleotide probes.

Keywords :
  • AUTOIMMUNE DISEASES
  • BIOMARKERS
  • EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS
  • IMMUNE THERAPY
  • MULTIPLE SCLEROSIS
  • PROTEOMICS
  • RHEUMATOID ARTHRITIS
  • T-CELL VACCINATION

Responsible :
Piet STINISSEN

Members of the research group :

Amber ARAIN
Rebeca ARROYO HORNERO
Paulien BAETEN
Angela BALOCCO
Sven BAMPS
Joel BEAUMONT
Lien BECKERS
Rob BIELEN
Josianne BLEUS
Christel BOCKEN
Jeroen BOGIE
Bieke BROUX
Dana BUSSCHOTS
Ina CALLEBAUT
Janneke COX
Valentino D'ONOFRIO
Eefje DERCON
Elien DERVEAUX
Anne-Marie DESCAMPS
Tess DIERCKX
Laura DUSAER
Beatriz FERNANDES CORTE-REAL
Judith FRAUSSEN
Guy FROYEN
Aida GARCIA CORRALES
Piet GEUSENS
Anneleen GEUZENS
Lotte GEYS
Elien GRAJCHEN
Inge GYSSENS
Mansour HAIDAR
Ibrahim HAMAD
Niels HELLINGS
Jerome HENDRIKS
Doryssa HERMANS
Leen HEYENS
Cindy HOEKS
Baharak HOSSEINKHANI
Monique HOSSELET
Evelien HOUBEN
Joy IROBI
Jaak JANSSENS
Markus KLEINEWIETFELD
Ozgur KOC
Philippos KOULOUSAKIS
Soren KUYPERS
Joy LODEWIJCKX
Melanie LOIX
Silke LOYENS
Koen MAGERMAN
Guy MASSA
Johan MATHIJS
Rut MAZON CABRERA
Jeroen MEBIS
Theo MEERT
Liesbet MESOTTEN
Dieter MESOTTEN
Peter MESSIAEN
Luc MICHIELS
Annelie MONNIER
Gwendoline MONTES DIAZ
Revathy MUNUSWAMY
Jean-Paul NOBEN
BĂ©nedith OBEN
Dean PAES
Liesbet PEETERS
Toon PEETERS
Joris PENDERS
Elisabeth PICCART
Ashkan PIRMANI
Astrid PUES
Dana QUADEN
Marc RAES
Raul RAMOS PUPO
Iris RENIERS
Geert ROBAEYS
Jolien ROBIJNS
Ben ROMBAUT
Jean-Luc RUMMENS
Igna RUTTEN
Pieter RUYTINX
Sotheary SANN
Melissa SCHEPERS
Leen SLAETS
Veerle SOMERS
Piet STINISSEN
Dries SWINNEN
Michiel THOMEER
Assia TIANE
Marie-Paule TULLENERS
Sam VAN BOXSTAEL
Annet VAN DE WATERWEG BERENDS
Joop VAN DEN BERGH
Bram VAN DEN BROEK
Jeroen VAN DER HILST
Fran VAN HEUVERSWYN
Jack VAN HORSSEN
Lauren VAN ZEEBROECK
Patrick VANDORMAEL
Pascal VANELDEREN
Kimberly VANHEES
Sam VANHERLE
Sarah VANHERLE
Karolien VANHOVE
Tim VANMIERLO
Veronique VASTMANS
Laura VISCONTI
An VOETS
Katrien WAUTERICKX
Katrien WIJNEN
Ralf WILLEBRAND
Leen WILLEMS
David WILSON
Elien WOUTERS
Femke WOUTERS
Jan YPERMAN



Projects of the research group 


Publications of the research group 


More information : http://www.uhasselt.be/UH/Onderzoeksgroepen/DetOndgr.html?oid=43