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ANNELIES BRONCKAERS

 Annelies Bronckaers (°1982) obtained her degree of Master in Biological sciences (2004) at the Katholieke Universiteit Leuven (KULeuven), Belgium. In 2009, she received her PhD at the Rega Institute ( KULeuven) where she studied the role of thymidine phosphorylase and thymidine phosphorylase inhibitors in angiogenesis. During this period, she went two times abroad to work at foreign laboratories: Oxford (UK), (the Division of Structural Biology of Prof. DK Stammers) and to Bari (Italy) (group of Prof. D. Ribatti). From 1st of November 2009 until September 2016, Annelies Bronckaers had a postdoc position at the UHasselt, in the laboratory of Prof.I. Lambrichts. This research group is specialized in the use of dental stem cells for bone and nerve regeneration. At that time, the focus of her research was the application of dental stem cells to improve angiogenesis and neuroregeneration. Since the 1st of October 2016, Annelies Bronckaers has a tenure track position at Hasselt University. She is specialized in cellular, embryonic and mouse models to study angiogenesis and tissue regeneration, stem cell differentiation, signal pathway analysis and electron microscopy. Her small new research group currently consists of 2 PhD students focusing on the use of engineered dental pulp stem cells as therapy in diseases where angiogenesis is insufficient such as ischemic stroke or hindlimb ischemia. In addition, she is participating at a VLIR-UOS project between Uhasselt (Prof. B. Brône) and to study the effect of low-frequency electromagnetic field in stroke therapy. Her research is funded by the FWO. According to the Web of Knowledge on 23th of March 2017, Annelies Bronckaers has a h-index of 16, is co-author of 30 peer-reviewed articles which were in total 559 times cited.

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Key publications

  • Struys T, Govaerts K, Oosterlinck W, Casteels C, Bronckaers A, Koole M, Van Laere K, Herijgers P, Lambrichts I, Himmelreich U, Dresselaers T.(2017) In vivo evidence for long-term vascular remodeling resulting from chronic cerebral hypoperfusion in mice. J Cereb Blood Flow Metab. 37(2):726-739. doi: 10.1177/0271678X16638349. (IF: 4.9)
  • Ratajczak J, Hilkens P, Gervois P, Wolfs E, Jacobs R, Lambrichts I, Bronckaers A (2016)  Angiogenic Capacity of Periodontal Ligament Stem Cells Pretreated with Deferoxamine and/or Fibroblast Growth Factor-2. PLoS One. 2016 Dec 9;11(12):e0167807. doi: 10.1371/journal.pone.0167807. (IF: 4.41)
  • Ratajczak J*, Bronckaers A*, Dillen Y, Gervois P, Vangansewinkel T, Driesen RB, Wolfs E, Lambrichts I, Hilkens P. (2016) The Neurovascular Properties of Dental Stem Cells and Their Importance in Dental Tissue Engineering. Stem Cells International. 2016:9762871. doi: 10.1155/2016/9762871. (IF: 3.68) *shared first author
  • Gervois P, Wolfs E, Ratajczak J, Dillen Y, Vangansewinkel T, Hilkens P, Bronckaers A, Lambrichts I, Struys T.(2016) Stem Cell-Based Therapies for Ischemic Stroke: Preclinical Results and the Potential of Imaging-Assisted Evaluation of Donor Cell Fate and Mechanisms of Brain Regeneration. Medicinal Research Reviews. 36(6):1080-1126. doi: 10.1002/med.21400. (IF: 9.13)
  • Ravanidis S, Bogie JF, Donders R, Craeye D, Mays RW, Deans R, Gijbels K, Bronckaers A, Stinissen P, Pinxteren J, Hellings N (2015) Neuroinflammatory signals enhance the immunomodulatory and neuroprotective properties of multipotent adult progenitor cells. Stem Cell Research and Therapeutics. 16;6:176. doi: 10.1186/s13287-015-0169-z. (IF: 4.5)
  • Bronckaers, A., Hilkens, P., Martens, W., Gervois, P., Ratajczak, J., Struys, T., & Lambrichts, I. (2014). Mesenchymal stem/stromal cells as a pharmacological and therapeutic approach to accelerate angiogenesis. Pharmacol Ther, 143, 181-196.(IF:9.723 , citations: 53)
  • Hilkens, P., Fanton, Y., Martens, W., Gervois, P., Struys, T., Politis, C., Lambrichts, I., & Bronckaers, A. (2014). Pro-angiogenic impact of dental stem cells in vitro and in vivo. Stem Cell Research, 12, 778-790. (IF: 3.78)
  • Martens W, Sanen K, Georgiou M, Struys T, Bronckaers A, Ameloot M, Phillips J, Lambrichts I. (2013) ‘Human dental pulp stem cells can differentiate into Schwann cells and promote and guide neurite outgrowth in an aligned tissue-engineered collagen construct in vitro.’ FASEB J. 2013 (IF: 5.7)
  • Bronckaers, A., Hilkens, P., Fanton, Y., Struys, T., Gervois, P., Politis, C., Martens, W., & Lambrichts, I. (2013). Angiogenic properties of human dental pulp stem cells. PLoS One, 8, e71104. (IF:4.0,  citations: 37)
  • Hilkens P, Gervois P, Fanton Y, Vanormelingen J, Martens W, Struys T, Politis C, Lambrichts I,Bronckaers A. (2013) ‘Effect of isolation methodology on stem cell properties and multilineage differentiation potential of human dental pulp stem cells’ Cells and Tissue Research’ 353:65-78. (IF: 3.6)

 

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