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Healthy Aging - An Euregional opportunity

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PROJECT PARTNER 6: GLYCOCHECK

GlycoCheck has developed a fully automated, noninvasive measurement system to assess the condition of the endothelial glycocalyx in patients and healthy individuals, based on microscopic imaging analysis of videos of the sublingual microvasculature using patented glycocalyx analysis software.

The glycocalyx is an important compartment of the luminal surface of the vascular endothelial lining that mediates interaction with circulating blood cells and that protects our circulatory system against pathogenic challenges like cholesterol and hyperglycemia.

The glycocalyx measurement system is used in over 40 international clinical studies and demonstrated that glycocalyx damage reflects early vascular vulnerability in patients exposed to cardiovascular risk factors. Furthermore, it has become clear that glycocalyx health is affected by aging and that age dependent modification of the glycocalyx can be used as a marker to monitor the impact of inflammatory disease and immune aging

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