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For Researchers

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Researchers of the ENVIRONAGE birth cohort and follow-up study include PhD students working on their doctoral thesis, and postdoctoral researchers. Results are published in international peer-reviewed journals, which can be accessed through PUBMED.

Publication years: 2012, 2013, 2014, 2015, 2016, 2017, 2018, 2019

List was updated February 27th, 2019.



  • Prenatal particulate air pollution exposure and cord blood homocysteine in newborns: Results from the ENVIRONAGE birth cohort
    Hogervorst JGF, Madhloum N, Saenen ND, Janssen BG, Penders J, Vanpoucke C, De Vivo I, Vrijens K, Nawrot TS.
    Environ Res 2019 Jan; 168:507-513. doi: 10.1016/j.envres.2018.08.032



  • Ageing at the level of telomeres in association to residential landscape and air pollution at home and work: a review of the current evidence
    Martens DS, Nawrot TS.
    Toxicol Lett 2018 Dec 1; 298:42-52; doi: 10.1016/j.toxlet.2018.06.1213


  • Sex-specific associations between telomere length and candidate miRNA expression in placenta
    Tsamou M, Martens DS, Cox B, Madhloum N, Vrijens K, Nawrot TS.
    J Transl Med 2018 Sep 12; 16(1):254. doi: 10.1186/s12967-018-1627-z


  • Air pollution and the fetal origin of disease: A systematic review of the molecular signatures of air pollution exposure in human placenta
    Luyten LJ, Saenen ND, Janssen BG, Vrijens K, Plusquin M, Roels HA, Debacq-Chainiaux F, Nawrot TS.
    Environ Res 2018 Jun 13; 166:310-323; doi: 10.1016/j.envres.2018.03.025


  • Placental promoter methylation of DNA repair genes and prenatal exposure to particulate air pollution: an ENVIRONAGE cohort study
    Neven KY, Saenen ND, Tarantini L, Janssen BG, Lefebvre W, Vanpoucke C, Bollati V, Nawrot TS.
    Lancet Planet Health 2018 Apr 4; 2(4):e174-e183; doi: 10.1016/S2542-5196(18)30049-4


  • DNA methylome marks of exposure to particulate matter at three time points in early life
    Plusquin M, Chadeau-Hyam M, Ghantous A, Alfano R, Bustamante M, Chatzi L, Cuenin C, Gulliver J, Herceg Z, Kogevinas M, Nawrot TS, Pizzi C, Porta D, Relton CL, Richiardi L, Robinson O, Sunyer J, Vermeulen R, Vriens A, Vrijheid M, Henderson J, Vineis P.
    Environ Sci Techn Apr 11;  doi: 10.1021/acs.est.7b06447


  • Placental circadian pathway methylation and in utero exposure to fine particulate air pollution
    Nawrot TS, Saenen ND, Schenk J, Janssen BG, Motta V, Tarantini L, Cox B, Lefebvre W, Vanpoucke C, Maggioni C, Bollati V.
    Environ Int 2018 Mar 7; 114(231-241) doi: 10.1016/j.envint.2018.02.034


  • Placental hypoxia-regulating network in relation to birth weight and ponderal index: the ENVIRONAGE Birth Cohort Study
    Vrijens K, Tsamou M, Madhloum N, Gyselaers W, Nawrot TS.
    J Transl Med 2018 Jan 10; 16(1):2. doi: 10.1186/s12967-017-1375-5



  • Prenatal Air Pollution and Newborns' Predisposition to Accelerated Biological Aging
    Martens DS, Cox B, Janssen BG, Clemente DBP, Gasparrini A, Vanpoucke C, Lefebvre W, Roels HA, Plusquin M, Nawrot TS.
    JAMA Pediatr 2017; doi: 10.1001/jamapediatrics.2017.3024


  • Recent versus chronic fine particulate air pollution exposure as determinant of the retinal microvasculature in school children
    Provost EB, Int Panis L, Saenen ND, Kicinski M, Louwies T, Vrijens K, De Boever P, Nawrot TS
    Environ Res 2017; 159 :103-110 doi: 10.1016/j.envres.2017.07.027.


  • Mother's Pre-pregnancy BMI and Placental Candidate miRNAs: Findings from the ENVIRONAGE Birth Cohort
    Tsamou M, Martens DS, Winckelmans E, Madhloum N, Cox B, Gyselaers W, Nawrot TS, Vrijens K
    Sci Rep 2017; 7(1) :5548 DOI: 10.1038/s41598-017-04026-8


  • Regulating role of fetal thyroid hormones on placental mitochonrial DNA methylation: epidemiological evidence from the ENVIRONAGE birth cohort study
    Janssen BG, Byun HM, Roels HA, Gyselaers W, Penders J, Baccarelli AA, Nawrot TS
    Clin Epigenetics 2017; 9 :66. DOI: 10.1186/s13148-017-0366-y


  • Blood pressure in young adulthood and residential greenness in the early-life environment of twins
    Bijnens EM, Nawrot TS, Loos RJ, Gielen M, Vlietinck R, Derom C, Zeegers MP.
    Environ Health 2017; 16(1) :53. DOI: 10.1186/s12940-017-0266-9


  • Newborn sex-specific transcriptome signatures and gestational exposure to fine particles: findings from the ENVIRONAGE birth cohort
    Winckelmans E, Vrijens K, Tsamou M, Janssen BG, Saenen ND, Roels HA, Kleinjans J, Lefebvre W, Vanpoucke C, de Kok TM, Nawrot TS
    Environ Health 2017; 16(1) :52. DOI: 10.1186/s12940-017-0264-y


  • Cord plasma insulin and in utero exposure to ambient air pollution
    Madhloum N, Janssen BG, Martens DS, Saenen ND, Bijnens E, Gyselaers W, Penders J, Vanpoucke C, Lefebvre W, Plusquin M, Nawrot TS.
    Environ Int 2017; 105 :126-132. DOI: 10.1016/j.envint.2017.05.012


  • Cohort Profile: The ENVIRonmental influence ON early AGEing (ENVIRONAGE): a birth cohort study
    Janssen BG, Madhloum N, Gyselaers W, Bijnens E, Clemente DB, Cox B, Hogervorst J, Luyten L, Martens DS, Peusens M, Plusquin M, Provost EB, Roels HA, Saenen ND, Tsamou M, Vriens A, Winckelmans E, Vrijens K, Nawrot TS.
    Int J Epidemiol 2017; In Press. DOI: 10.1093/ije/dyw269


  • Placental Mitochondrial DNA and CYP1A1 gene methylation as molecular signatures for tobacco smoke exposure in pregnant women and the relevance for birth weight
    Janssen BG, Gyselaers W, Byun HM, Roels HA, Cuypers A, Baccarelli AA, Nawrot TS.
    J Transl Med 2017; 15(1) :5. DOI: 10.1186/s12967-016-1113-4 


  • Fetal Thyroid Function, Birth Weight, and in Utero Exposure to Fine Particle Air Pollution: A Birth Cohort Study
    Janssen BG, Saenen ND, Roels HA, Madhloum N, Gyselaers W, Lefebvre W, Penders J, Vanpoucke C, Vrijens K, Nawrot TS.
    Environ Health Perspect 2017; 125(4) : 699-705. DOI: 10.1289/EHP508


  • Lower Placental Leptin Promoter Methylation in Association with Fine Particulate Matter Air Pollution during Pregnancy and Placental Nitrosative Stress at Birth in the ENVIRONAGE Cohort
    Saenen ND, Vrijens K, Janssen BG, Roels HA, Neven KY, Vanden Berghe W, Gyselaers W, Vanpoucke C, Lefebvre W, De Boever P, Nawrot TS.
    Environ Health Perspect 2017;125(2) :262-268. DOI: 10.1289/EHP38


  • Neonatal Cord Blood Oxylipins and Exposure to Particulate Matter in the Early-Life Environment: An ENVIRONAGE Birth Cohort Study
    Martens DS, Gouveia S, Madhloum N, Janssen BG, Plusquin M, Vanpoucke C, Lefebvre W, Forsberg B, Nording M, Nawrot TS.
    Environ Health Perspect 2017; 125(4) :691-698. DOI: 10.1289/EHP291



  • Maternal pre-pregnancy body mass index and newborn telomere length
    Martens DS, Plusquin M, Gyselaers W, De Vivo I, Nawrot TS.
    BMC Med 2016; 14(1) :148. DOI: 10.1186/s12916-016-0689-0


  • Placental Nitrosative Stress and Exposure to Ambient Air Pollution During Gestation: A Population Study
    Saenen ND, Vrijens K, Janssen BG, Madhloum N, Peusens M, Gyselaers W, Vanpoucke C, Lefebvre W, Roels HA, Nawrot TS. 
    Am J Epidemiol 2016;184(6) :442-449. DOI: 10.1093/aje/kww007


  • Air pollution-induced placental epigenetic alterations in early life: a candidate miRNA approach
    Tsamou M, Vrijens K, Madhloum N, Lefebvre W, Vanpoucke C, Nawrot TS.
    Epigenetics. 2016; 22:0. DOI: 10.1080/15592294.2016.1155012


  • Small for gestational age and exposure to particulate air pollution in the early-life environment of twins
    Bijnens EM, Derom C, Gielen M, Winckelmans E, Fierens F, Vlietinck R, Zeegers MP, Nawrot TS.
    Environ Res 2016; 148: 39-45. DOI: 10.1016/j.envres.2016.03.006


  • Mitochondrial oxidative DNA damage and exposure to particulate air pollution in mother-newborn pairs
    Grevendonk L, Janssen BG, Vanpoucke C, Lefebvre W, Hoxha M, Bollati V, Nawrot TS. 
    Environ Health 2016; 20;15(1):10. DOI: 10.1186/s12940-016-0095-2


  • Prenatal ambient air pollution, placental mitochondrial DNA content, and birth weight in the INMA (Spain) and ENVIRONAGE birth cohort
    Clemente DB, Casas M, Vilahur N, Begiristain H, Bustamante M, Carsin AE, Fernández MF, Fieren F, Gyselaerts W, Iñiguez C, Janssen BG, Lefebre W, Llop S, Olea N, Pedersen M, Pieters N, Santa Marina L, Souto A, Tardón A, Vanpoucke C, Vrijheid M, Sunyer K, Nawrot TS.
    Environ Health Perspect 2016; 124(5): 659-665. DOI: 10.1289/ehp.1408981



  • Placental mitochondrial methylation and exposure to airborne particulate matter in the early life environment: An ENVIRONAGE birth cohort study
    Janssen BG, Byun HM, Gyselaers W, Lefebvre W, Baccarelli AA, Nawrot TS.
    Epigenetics 2015; 10(6): 536-544. DOI: 10.1080/15592294.2015.1048412


  • In Utero Fine Particle Air Pollution and Placental Expression of Genes in the Brain-Derived Neurotrophic Factor Signaling Pathway: An ENVIRONAGE Birth Cohort Study
    Saenen ND, Plusquin M, Bijnens E, Janssen BG, Gyselaers W, Cox B, Fierens F, Molenberghs G, Penders J, Vrijens K, De Boever P, Nawrot TS.
    Environ Health Perspect 2015; 123(8): 834-840. DOI: 10.1289/ehp.1408549


  • Lower placental telomere length may be attributed to maternal residential traffic exposure; a twin study
    Bijnens EM, Zeegers MP, Gielen M, Kicinski M, Hageman GJ, Pachen D, Derom C, Vlietinck R, Nawrot TS.
    Environ Int 2015; 79: 1-7. DOI: 10.1016/j.envint.2015.02.008



  • Variation of DNA methylation in candidate age-related targets on the mitochondrial-telomere axis in cord blood and placenta.
    Janssen BG, Byun HM, Cox B, Gyselaers W, Izzi B, Baccarelli AA, Nawrot TS.
    Placenta 2014; 35: 665-672. DOI: 10.1016/j.placenta.2014.06.371


  • Placental DNA hypomethylation in association with particulate air pollution in early life.
    Janssen BG, Godderis L, Pieters N, Poels K, Kicinski M, Cuypers A, Fierens F, Penders J, Plusquin M, Gyselaers W, Nawrot TS. 
    Part Fibre Toxicol 2013; 10: 22. DOI: 10.1186/1743-8977-10-22



  • Placental mitochondrial DNA content and particulate air pollution during in utero life
    Janssen BG, Munters E, Pieters N, Smeets K, Cox B, Cuypers A, Fierens F, Penders J, Vangronsveld J, Gyselaers W, Nawrot TS. 
    Environ Health Perspect 2012; 120: 1346-1352. DOI: 10.1289/ehp.1104458