European Joint Programming (EJP) on Rare Diseases - call 2022
Research
Funding organisation:
Fonds voor Wetenschappelijk Onderzoek - Vlaanderen
What?
A new joint transnational call for research projects is open, in the framework of the ‘EJP on Rare Diseases’, an elaborate programme which focusses on the broad rare diseases thematic, both on a European and international level.
This specific call focuses on ‘Development of new analytic tools and pathways to accelerate diagnosis and facilitate diagnostic monitoring of rare diseases’.
At least one of the following topics of the call have to be addressed in a research project:
- Phenotype-driven diagnosis: integration across different ontologies, integration of shared pathways, digital phenotyping, development of artificial intelligence approaches/applications to extract health related data in aid of diagnosis.
- Prognostic markers/biomarkers investigations for early diagnosis and monitoring.
- Methodologies for solving cases that are currently difficult to analyze due to different underlying mechanisms (e.g., mosaicism, genomic (non-coding) alterations, gene regulation, complex inheritance), including new genomics / functional genomics technologies, multi-omics, mathematics, biostatistics, bioinformatics and artificial intelligence approaches.
- Functional strategies to globally stratify variants of unknown significance (VUS) for clinical use; setting up of (in vitro) systems to distinguish between VUS and pathogenic variants (e.g., confirming disruption of splicing for deep intronic variants, loss of protein function, and gain of toxic protein function).
- Development of pathway models to enable diagnosis, especially for newly discovered diseases that may share underlying molecular mechanisms with already known diseases.
Application?
Both the FWO (junior/senior) research project (FO) and Strategic Basic Research (SBO) funding channels are integrated within this call. The type and scope of the proposed research project will determine the choice of funding channel for the research from within Flanders. Non-compliance with the specific requirements per funding channel will inevitably lead to non-eligibility.
For Flanders it is possible to participate via the Research Foundation Flanders (FWO). The FWO provides funding of € 350.000 per project of 3 years in the following ways:
- Fundamental Research Projects (junior/ senior FO): The regulations for the research project are applied here, more information on these regulations can be found here. For Fundamental Research Projects, the standard overhead percentage of 6% is included in the maximum requested budget of € 350.000.
- Strategic Basic Research (SBO): The regulations for the Strategic Basic Research are applied here, more information on these regulations can be found here. For Strategic Basic Research, the SBO-specific overhead rules must be taken into account. The cost-model document is available here.
When the subproject from Flanders implies an SBO project the researchers are asked to provide proactively, and before the pre-proposal submission deadline, a concise – but to the point – valorisation plan to the FWO (no fixed format, max. 1-2 A4-pages), which i) clarifies the valorisation context within Flanders (and internationally eventually), and ii) mentions the interested and involved actors from Flanders. This document can be sent towards the eranet@fwo.be email address.
The EJP E-RARE Call is a two step call. The consortium must submit their proposal via EJP Electronic submission system:
- Pre-proposal submission deadline: 16th February 2022
- Full proposal submission deadline: 15th June 2022
More information?
More information on this call can be found on the website of EJP or on the website of the FWO.
The EJP had organised a webinar on 16 December 2021. The webinar wasn't recorded, however the presentation and Q&A was made available.
Deadline
15.06.2022
Contact Hasselt University?
E-mail helen.cheng@uhasselt.be