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BIOMED

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BART VAN WIJMEERSCH

Bart Van Wijmeersch, MD, PhD (°1976) is a neurologist-immunologist with subspecialisation in Multiple Sclerosis. He completed his general medical training in 2001 at the University Of Leuven (KUL), after which he started his specialization in Neurology. During this residency he started a PhD in neuroimmunology at the lab of experimental transplantation and neuroimmunology at the KUL. He was promoted in 2008 with a thesis entitled: ' Graft-versus-autoimmunity after induction of mixed bone marrow chimerism in murine models of experimental autoimmune encephalomyelitis'.  Since 2008, he is active as neurologist, specialized in Multiple Sclerosis (MS), at the Rehabilitation & MS-Centre in Overpelt, where he leads a multidisciplinary team for MS, and is the Medical Director of the Centre.
He’s an associate Professor at the University of Hasselt, where he’s involved in pre-clinical as well as the clinical research on MS at the biomedical institute (BIOMED). He has a supporting role in all the immunological research on blood- and CSF samples of persons with MS and in EAE-animal models, as well as in the rehabilitation research at REVAL. Immunological, Biomaker, MRI, Electrophysiological and Rehabilitation research in MS come together in this way. He has an educational role in the faculty of medicine and physiotherapy.
He’s a member of the Belgian Study Group of Multiple Sclerosis and a member of advisory boards of different pharmaceutical companies with interest in Multiple Sclerosis.

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Key Publications

  • Van Wijmeersch B, Sprangers B, Rutgeerts O, Lenaerts C, Landuyt W, Waer M, Billiau AD, Dubois B. Allogeneic bone marrow transplantation in models of experimental autoimmune encephalomyelitis: evidence for a graft-versus-autoimmunity effect. Biol Blood Marrow Transplant. 2007 Jun;13(6):627-37.
  • Broux B, Pannemans K, Zhang X, Markovic-Plese S, Broekmans T, Eijnde BO, Van Wijmeersch B, Somers V, Geusens P, van der Pol S, van Horssen J, Stinissen P, Hellings N. CX(3)CR1 drives cytotoxic CD4(+)CD28(-) T cells into the brain of multiple sclerosis patients. J Autoimmun. 2012 Feb;38(1):10-9.
  • Lamers I, Kerkhofs L, Raats J, Kos D, Van Wijmeersch B, Feys P. Perceived and actual arm performance in multiple sclerosis: relationship with clinical tests according to hand dominance. Mult Scler. 2013 Sep;19(10):1341-8.
  • de Bock L, Somers K, Fraussen J, Hendriks JJ, van Horssen J, Rouwette M, Hellings N, Villar LM, Alvarez-Cermeño JC, Espiño M, Hupperts R, Jongen P, Damoiseaux J, Verbeek MM, De Deyn PP, D'hooghe M, Van Wijmeersch B, Stinissen P,  Somers V. Sperm-associated antigen 16 is a novel target of the humoral autoimmune response in multiple sclerosis. J Immunol. 2014 Sep 1;193(5):2147-56.
  • Cuypers K, Leenus DJ, Van Wijmeersch B, Thijs H, Levin O, Swinnen SP, Meesen RL. Anodal tDCS increases corticospinal output and projection strength in multiple sclerosis. Neurosci Lett. 2013 Oct 25;554:151-5.
  • Fraussen J, Vrolix K, Claes N, Martinez-Martinez P, Losen M, Hupperts R, Van Wijmeersch B, Espiño M, Villar LM, De Baets MH, Stinissen P, Somers V. Autoantigen induced clonal expansion in immortalized B cells from the peripheral blood of multiple sclerosis patients. J Neuroimmunol. 2013 Aug 15;261(1-2):98-107.
  • Rouwette M, Noben JP, Van Horssen J, Van Wijmeersch B, Hupperts R, Jongen PJ, Verbeek MM, De Deyn PP, Stinissen P, Somers V. Identification of coronin-1a as a novel antibody target for clinically isolated syndrome and multiple sclerosis. J  Neurochem. 2013 Aug;126(4):483-92.
  • Lamers I, Timmermans AA, Kerkhofs L, Severijns D, Van Wijmeersch B, Feys P. Self-reported use of the upper limbs related to clinical tests in persons with multiple sclerosis. Disabil Rehabil. 2013;35(23):2016-20.
  • Thewissen K, Nuyts AH, Deckx N, Van Wijmeersch B, Nagels G, D'hooghe M, Willekens B, Cras P, Eijnde BO, Goossens H, Van Tendeloo VF, Stinissen P, Berneman ZN, Hellings N, Cools N. Circulating dendritic cells of multiple sclerosis patients are proinflammatory and their frequency is correlated with MS-associated genetic risk factors. Mult Scler. 2014 Apr;20(5):548-57.
  • Pannemans K, Broux B, Goris A, Dubois B, Broekmans T, Van Wijmeersch B, Geraghty D, Stinissen P, Hellings N. HLA-E restricted CD8+ T cell subsets are phenotypically altered in multiple sclerosis patients. Mult Scler. 2013 Oct 21.
  • Neven A, Janssens D, Alders G, Wets G, Van Wijmeersch B, Feys P. Documenting outdoor activity and travel behaviour in persons with neurological conditions using travel diaries and GPS tracking technology: a pilot study in multiple sclerosis. Disabil Rehabil. 2013 Sep;35(20):1718-25.
  • Rouwette M, Somers K, Govarts C, De Deyn PP, Hupperts R, Van Wijmeersch B, De Jong BA, Verbeek MM, Van Pesch V, Sindic C, Villar LM, Álvarez-Cermeño JC, Stinissen P, Somers V. Novel cerebrospinal fluid and serum autoantibody targets for clinically isolated syndrome. J Neurochem. 2012 Nov;123(4):568-77.

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