Project R-14319

Dose findings studies for tailored physical and cognitive-motor rehabilitation interventions for persons with MS (Research)

MS rehabilitation has changed dramatically based on the belief that an active lifestyle and participation in exercise programs can be neuroprotective or maximize function. Nevertheless, participation is often hampered by fatigue and other MS-related symptoms that make it difficult to manage exercise intensity: patients often show a discrepancy between their actual physiological state and their selfperception, possibly due to damage in the neural network that supports interoception. The aim of this project is to develop a paradigm to assess exercises relevant to daily life in an automated but safe and reliable manner through state-of-the-art rehabilitation technology and greater patient involvement. First, we will define technical solutions to monitor motor performance (walking, functional transitional movements) and to inform the person with MS when normal movement thresholds are exceeded. Second, we will conduct case series studies in controlled and uncontrolled environments.

16 September 2023 - 15 September 2027