Project R-15112

Comprehensive multidimensional assessment of gait adaptability as a marker of subtle gait deficits in persons multiple sclerosis with no to mild disability (Research)

Multiple sclerosis (MS) is a chronic neurological disease characterized by sensorimotor deficits, cognitive impairment, and fatigue, leading to disability. Walking and fear of falling is a major concern for persons with MS. A key component of maintaining safe mobility in daily life is the ability to adapt to the changing environment in a pro- or reactive manner. So far, proactive and reactive gait adaptability problems and mechanisms are not well understood in the MS population. Additionally, the validity and reliability of the clinical gait adaptability tests have not been known. Overall, this project aims to gain insights into the mechanism of gait adaptability by combining behavioral and neural outcomes, paving the way for tailored rehabilitation to improve the gait adaptability in MS. Furthermore, it aims to explore validity and reliability of the clinical gait adaptability tests in MS population.

16 October 2024 - 15 October 2026