Cardio & organ systems

Expertise

The Cardiology and Organ Systems (COST) research group focuses on in vitro and in vivo cellular and animal models in different fields such as cardiovascular disease, oncology and neurological disorders. These include the use of different stem cell types (embryonal, iPSC, DPSC, CASCs) and animal models of diastolic and systolic heart failure, cancer, peripheral neuropathies and ischemic stroke. These models are used to design and develop therapeutic applications in e.g. cancer and myocardial infarction or to unravel underlying disease mechanisms e.g. the role of AGEs and extracellular vesicles in cardio- and cerebrovascular disease. In addition to (stem) cell-based therapies, the effect of exercise as a medicine to improve the cardiometabolic status in various neurodegenerative, cardiovascular and respiratory diseases as well as in diabetes is studied. In general, the underlying biomedical/biomolecular mechanisms are investigated in animal models and human subjects using proteomic, genomic and bionanotechnology approaches.  This enables us to identify biomarker signatures (e.g. extracellular vesicles containing biomarkers) associated with the disease status or to monitor successful therapies. Thanks to the close collaboration with Reval, the Jessa Hospital and ZOL, we have the unique opportunity to combine basic research and clinical research and to translate acquired knowledge into clinical practice

Keywords

Advanced glycation end products, Angiogenesis, Cancer, Cardiovascular disease, Diabetes, Exercise intervention, Extracellular vesicles, Heart Ischemia, Ischemic stroke, Stem cells

Responsible

Annelies BRONCKAERS

Staff members

  • Ruth ACHTEN
  • Daniel AFRIFA
  • Lotte ALDERS
  • Sibel ALTINTAS
  • Myrte BARTHELS
  • Yoann BATAILLE
  • Youri BEKHUIS
  • Amy BELBA
  • Johan BELLEMANS
  • Edouard BENIT
  • Philippe BERTRAND
  • Virginie BITO
  • Annelies BRONCKAERS
  • Pieter CAEKEBEKE
  • Nuran CAZ
  • Marithe CLAES
  • Guido CLAESSEN
  • Jade CLAESSENS
  • William COLYN
  • Maarten CRIEL
  • Jeroen DAUW
  • Iris DE LAAT
  • Jarne DE PAEPE
  • Sebastien DEFERM
  • Dorien DELUYKER
  • Paul DENDALE
  • Jo DENS
  • Lien DESTEGHE
  • Sarah D'HAESE
  • Sebastiaan DHONT
  • Nathalie DHONT
  • Inge DIERICKX
  • Nathalie DIRKX
  • Pauline DREESEN
  • Ronald DRIESEN
  • Maarten FALTER
  • Wouter FRANSSEN
  • Pascal GERVOIS
  • Olivier GHEKIERE
  • Henri GRUWEZ
  • Wilfried GYSELAERS
  • Sibren HAESEN
  • Steffie HASEVOETS
  • Ellen HEEREN
  • Hein HEIDBUCHEL
  • Marc HENDRIKX
  • Lieven HERBOTS
  • Florian HERMANS
  • Line HEYLEN
  • Sarah HOEDEMAKERS
  • Eline HOES
  • Ruben HOFFMANN
  • Michiel JACOBS
  • Marc JANS
  • Hanne JEURISSEN
  • Abdullah KAYA
  • Hannelore KEMPS
  • Hanne KINDERMANS
  • Sevda KIZILKILIC
  • Lieselotte KNAEPEN
  • Joep KNOL
  • Pieter KOOPMAN
  • Koen KUIPERS
  • Ganesh KUMARASAMY
  • Ivo LAMBRICHTS
  • Dorien LANSSENS
  • Karen LIBBERECHT
  • Joy LODEWIJCKX
  • Sandrina MARTENS
  • Jeroen MEBIS
  • Evelyne MEEKERS
  • Liesbet MESOTTEN
  • Jill MEYNEN
  • Luc MICHIELS
  • Sara MOURA FERREIRA
  • Amanda MOYA GOMEZ
  • Wilfried MULLENS
  • Ine NIESTE
  • Petra NIJST
  • Kim NIJSTEN
  • Rana ONDER
  • Hanne OOSTERBOS
  • Bert OP 'T EIJNDE
  • Loren PACKLE
  • Rik PAUWELS
  • Benjamin PETERS
  • Paula PINCELA LINS
  • Elke PIRLET
  • Laurent PISON
  • Laura PONSAERTS
  • Leen POPLEU
  • Jules POUKENS
  • Jolien ROBIJNS
  • David RUTTENS
  • Martijn SCHERRENBERG
  • Melanie SCHOUTTETEN
  • Gregory SERGEANT
  • Christophe SMEETS
  • Jan STASSEN
  • Job STOKS
  • Mathieu STRUYVE
  • Kristof THEVISSEN
  • Michiel THOMEER
  • Philippe TIMMERMANS
  • Jolien VAN DEN BOSCH
  • Kurt VAN DER SPEETEN
  • Gregory VAN GENECHTEN
  • Evelyne VAN KERCKHOVE
  • Koenraad VAN RENTERGHEM
  • Jeroen VANDENBRANDE
  • Wendy VANDENDRIES
  • Pieter VANDERVOORT
  • Tim VANGANSEWINKEL
  • Jen VANHERLE
  • Bert VANMIERLO
  • Lotte VASTMANS
  • Frederik VERBRUGGE
  • Eline VERGHOTE
  • Jan VERWERFT
  • Johan VIJGEN
  • Pascal VRANCKX
  • Esther WOLFS
  • Femke WOUTERS
  • Linqi XU

Publications

More info

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