"Understanding the assembly and maintenance of the second brain"
By focusing at the interface between gut physiology and developmental neurobiology we investigate the patterning and communication within the enteric nervous system, the gut brain. A common theme in our lab is to understand the role of enteric glial cells and faulty intestinal nerve circuits in the transition from gastrointestinal homeostasis to digestive diseases, cancer and brain disorders. To this end a variety of live cell imaging techniques (https://www.uhasselt.be/aomc) is combined with several in vitro and in vivo models and advanced genetic and molecular tools. Our lab is partially based at Maastricht University Medical Centre (MUMC+, The Netherlands) where we join forces with the group of Dr. Veerle Melotte.