Lipids in Brain Diseases Symposium 2025

12:00 – 13:00

Registration

13:00 – 13:15

Opening

Session 1

13:15 – 14:00

Keynote 1: Dr. Fei Yin (Arizona, USA)
Astrocytic Lipid Clearance in Neurodegeneration: from Mechanism to Therapeutic Strategy

14:00 – 14:20

Selected oral talk: Sascha J. Koppes-den Hertog
Cholesterol regulates astrocyte reactivity and is dysregulated by ApoE4

14:20 – 14:40

Selected oral talk: Marta Turri
Inhibition of stearoyl-CoA desaturase leads to fatty acid normalization, improved dendritic spine density and neuronal regulation in hippocampus of Alzheimer’s disease

14:40 – 15:00

Selected oral talk: Dr. Melissa Birol
Tau spreading orchestrates lipid export and metabolic vulnerability in Tauopathies

15:00 – 15:30

Coffee break

Session 2

15:30 – 16:15

Keynote 2: Prof. Dr. Stephan Kemp (Amsterdam, The Netherlands)
Adrenoleukodystrophy, Lipidomics, and Newborn Screening: Connecting Science and Society

16:15 – 17:00

Keynote 3: Dr. Rik van der Kant (Amsterdam, The Netherlands)
Coupling of Lipid Metabolism and Immune Function in Human iPSC-Derived Astrocytes

17:00 – 18:00

Reception

8:00 – 9:00

Registration

Session 1

9:00 - 9:45

Keynote 1: Prof. Dr. Agnès Nadjar (Bordeaux, France)
Neuroimmunology of Metabolic Resilience

9:45 – 10:05

Selected oral talk: Dr. Anil G Cashikar
Role of an oxysterol pathway in neuroinflammation and neurodegeneration

10:05 – 10:25

Selected oral talk: Dr. Julie Jacquemyn
Glucosylceramide induced ectosomes propagate pathogenic α-synuclein in Parkinson’s disease

10:25 – 10:50

Coffee break

Session 2

10:50 – 11:35

Keynote 2: Dr. Tess Dierckx (Stanford, USA)
Circadian Control of Oligodendroglial Metabolism

11.35 – 11:55

Selected oral talk: Dr. Sam Vanherle
Loss of CD36 disrupts OPC differentiation and remyelination in the brain via pro-inflammatory eicosanoid signaling

11:55 – 12:15

Selected oral talk: Dr. Tom van der Wel
Genetic and pharmacological inactivation of glycerophosphodiesterase GDE4 promotes oligodendrocyte differentiation and remyelination

12:15 – 13:30

Lunch

Session 3

13:30 – 13:50

Sponsor talk: Sciex 

13:50 – 14:35

Keynote 3: Prof. Dr. Ron Heeren (Maastricht, The Netherlands)
Spatial Lipidomics; Translational Research From Cells To Tissue

14:35 – 16:00

Poster session and break

16:00 – 16:45

Keynote 4: Prof. Dr. Özgun Gökce (Bonn, Germany)
Immune and Lipid Pathways in Brain Aging and Injury: Insights from Single-Cell and Spatial Transcriptomics

16:45 – 17:05

Selected oral talk: Dr. Andreia Gomes-Duarte
AAV-Delivered Anti-PC-OxPL Antibody Fragments: A Novel Therapeutic Approach to Target ALS

18:00

Conference dinner @Lac Bleu, Hasselt

8:00 – 9:00

Registration

Session 1

9:00 – 09:45

Keynote 1: Prof. Dr. Johan Swinnen (Leuven, Belgium)
Application of Lipidomics Technologies to Unravel Lipid Metabolic Changes Underlying Brain Diseases

9:45 – 10:05

Selected oral talk: Dr. Leandro Cruz Rodriguez
Fingolimod’s underlying mechanism of action: a multimodal biophysical study using model membranes

10:05 – 10:25

Selected oral talk: Dr. Melanie Loix 
UBE3A promotes foam cell formation and counters remyelination by targeting ABCA1 for proteasomal degradation

10:25 – 10:50

Coffee break

Session 2

10:50 – 11:10

Selected oral talk: Gema Muñoz González
Lipid profile of normal-appearing myelin in Multiple Sclerosis

11:10 – 11:55

Keynote 2: Prof. Dr. Klaus-Armin Nave (Göttingen, Germany)
Myelin Lipids in Brain Energy Metabolism

11:55 – 12:20

Prices and Closing Remarks