Prof. dr. Jelle HENDRIX

About Me
Research
Publications
Projects
Education
Contact

E-mail Jelle Copy e-mail

+3211269213 Campus Diepenbeek
Gebouw C
Office BMO-C002

Prof. dr. Jelle HENDRIX

Associate Professor

Faculty of Medicine and Life Sciences
Capacity group Neurosciences
Research group Neurosciences
Biomedical Research Institute

Membership

Ombuds (Plv.) Board of examination bachelor geneeskunde

About Me

head of the Dynamic Bioimaging Lab
manager of the Advanced Optical Microscopy Centre
researcher in the Biomedical Research Institute
complete publication list on Pubmed
scientific social network on Twitter and LinkedIN

Research

Discipline codes: Characterisation of biologically active (macro)molecules (01040402), Spectroscopic methods (01040107), Proteins (01060208), Molecular biophysics (03010402), Structural biology (03050304), Biophotonics (02070103), Analytical spectrometry (01040102), Intracellular compartments and transport (01060910), Soft condensed matter (01030410)

Supervised PhDs

Phase separation as a hallmark for toxic protein conversion in tauopathies

Pedro Silva for the title Doctor of Biomedical Sciences (doctorate in progress)

Supervised as Promotor

Single-molecule fluorescence-based realtime structural biology of the adenosine A2A G-protein coupled receptor in microfabricated cells

Stijn Dilissen for the title Doctor of Biomedical Sciences (doctorate in progress)

Supervised as Promotor

Substrate-Dependent Conformational Landscape of Human DNA Ligases

Tom Kache for the title Doctor of Biomedical Sciences (doctorate in progress)

Supervised as Promotor

Integrating coarse-grained molecular dynamics and fluorescence spectroscopy to unravel disordered protein condensates

Eva Punter for the title Doctor of Biomedical Sciences (doctorate in progress)

Supervised as Promotor

Thermal-probing microdevices to unravel phase separating condensates involved in neurodegeneration

Lambert-Paul Jorissen for the title Doctor of Engineering Technology (doctorate in progress)

Supervised as Copromotor

View all 9 supervised PhD's of Prof. dr. Jelle HENDRIX

Development and application of a combined fluorescence microscopy and microfluidics tool for characterizing biomolecular condensates

Yarne Vankerkhoven for the title Doctor of Biomedical Sciences (doctorate in progress)

Supervised as Promotor

Imaging strategies to investigate Glycine receptor splicing variant co-assembly and the impact on mobility and function

Veerle Lemmens for the title Doctor of Biomedical Sciences in 2024

Supervised as Promotor

Investigation of the conformational dynamics of G protein-coupled receptors using single-molecule fluorescence microscopy

Ivan Maslov for the title Doctor of Biomedical Sciences in 2023

Supervised as Promotor

Nanoplasmonic sensing platform for lectin detection

Alessia Pancaro for the title Doctor of Biomedical Sciences in 2023

Supervised as Promotor

View all 9 supervised PhD's of Prof. dr. Jelle HENDRIX

Publications

View all UHasselt publications by Prof. dr. Jelle HENDRIX

Projects

35 research projects have been found

Flanders BioImaging: Leading Imaging Application Integrated Service and Enablement (FBI-LIAISE) (Research)

01/01/2023 - 31/12/2026

MULTISCALE - The UHasselt MultiScale Optical Imaging Core: Infrastructure for nano- to centimeter length scale microscopy and analysis of 'big' 4D datasets (Research)

01/05/2022 - 30/04/2026

View all 35 UHasselt research projects of Prof. dr. Jelle HENDRIX

Structuromics@UHasselt - Experimental and theoretical platform for unravelling the spatiotemporal organisation of biomolecular assemblies (Research)

01/05/2025 - 30/04/2030

Integrating Coarse‐Grained Molecular Dynamics and Fluorescence Spectroscopy to Unravel Disordered Protein Condensates (Research)

01/11/2024 - 31/10/2028

Thermal-probing microdevices to unravel phase separating condensates involved in neurodegeneration (Research)

01/11/2024 - 31/10/2028

Thermal-probing microdevices to unravel phase separating condensates involved in neurodegeneration (Research)

01/11/2024 - 31/10/2028

Integrating Coarse‐Grained Molecular Dynamics and Fluorescence Spectroscopy to Unravel Disordered Protein Condensates (Research)

01/11/2024 - 31/10/2028

Beyond the biopsy: Innovative multimodal imaging to assess whole tumor heterogeneity in lung cancer (Research)

01/10/2025 - 30/09/2028

INSITE - A new combined experimental and theoretical framework for studying liquid protein condensates and its application to discover new targets for misfolded protein diseases (Research)

01/01/2024 - 31/12/2027

MULTISCALE - Infrastructure for nano- to centimeter length scale microscopy and big data analysis of optical imaging data (Research)

01/04/2022 - 31/03/2026

Protein folding/non-folding and dynamics (PROFOUND) (Research)

01/01/2021 - 31/12/2025

NATIVE - Single molecule optical microscopy and lipid nanotechnology 'ménage-à-deux' for deciphering multidrug transport in near-native environments (Research)

01/01/2022 - 31/12/2025

Substrate-Dependent Conformational Landscape of Human DNA Ligases (Research)

01/11/2023 - 31/10/2025

Single-molecule fluorescence-based realtime structural biology of the adenosine A2A G-protein coupled receptor in microfabricated cells (Research)

01/11/2023 - 31/10/2025

Single-molecule fluorescence-based realtime structural biology of the adenosine A2A G-protein coupled receptor in microfabricated cells (Research)

01/11/2021 - 31/10/2025

Substrate-Dependent Conformational Landscape of Human DNA Ligases (Research)

01/11/2021 - 31/10/2025

Unveiling molecular interactions through temperature-controlled microfluidic devices and fluorescence microscopy (Research)

01/10/2023 - 30/09/2025

Development of microdevices for screening membrane protein realtime structure in physiological conditions and investigation of multidrug resistance transporter LmrP (Research)

01/11/2021 - 31/10/2024

FABLITE – A light sheet microscopy and microfabrication 'ménage-àdeux' for real-time, high throughput and physiological structural biology. (Research)

01/10/2020 - 30/09/2024

Single-molecule structural investigations of tau protein (Research)

01/08/2020 - 31/07/2024

Marketable solution for advanced microscopy image correlation analysis. (Research)

01/03/2022 - 31/12/2023

Investigation of G-protein coupled receptors conformational dynamics via single-molecule fluorescence microscopy. (Research)

01/09/2021 - 31/12/2023

Single-molecule fluorescence-based realtime structural biology of the adenosine A2A G-protein coupled receptor in microfabricated cells (Research)

01/11/2021 - 31/10/2023

Substrate-Dependent Conformational Landscape of Human DNA Ligases (Research)

01/11/2021 - 31/10/2023

Development of microdevices for screening membrane protein realtime structure in physiological conditions and investigation of multidrug resistance transporter LmrP (Research)

01/11/2019 - 31/10/2023

FB-III ("FB triple-I") : Flanders BioImaging: Integrating Imaging Infrastructure from cell to man. (Research)

01/02/2021 - 31/01/2023

TRPV4 as a key driver of branch motility and somatic migration of microglial cells (Research)

01/10/2019 - 30/09/2022

Molecular dynamics and force generation: shedding new light on cell mechanosensing and communication (Research)

01/10/2018 - 30/09/2022

Development of microdevices for screening membrane protein realtime structure in physiological conditions and investigation of multidrug resistance transporter LmrP (Research)

01/11/2019 - 31/10/2021

Novel tools for dynamic structural biology (Research)

01/10/2020 - 12/10/2021

Biophotonics (Research)

01/01/2019 - 30/09/2021

Flanders BioImaging: towards an integrated, translational and multimodal imaging platform from molecule to man. (Research)

01/02/2019 - 31/01/2021

Single molecule Förster resonance energy transfer, and its application to ligand gated ion channel structure (Research)

01/01/2018 - 31/12/2020

Multipurpose multiphoton confocal laser scanning microscope (Research)

01/05/2016 - 30/04/2020

Patch-clamp fluorometry platform for unravelling the structure-function relationship of the GlyR (Research)

01/10/2017 - 31/03/2019

View all 35 UHasselt research projects of Prof. dr. Jelle HENDRIX

Education

Involved in the following courses

Academic year 2025 - 2026

3979

Advanced Light Microscopy

Coordinating lecturer

3748

Bachelor's thesis

Coordinating lecturer

3408

Biology of the Cell

Coordinating lecturer

3735

Heart & blood

Member of the teaching team

3620

Immunity

Member of the teaching team

3951

Innovative techniques in imaging

Coordinating lecturer

3738

Lung and kidney

Member of the teaching team

5483

Multidisciplinary biomedical research

Member of the teaching team

Academic year 2024 - 2025

3979

Advanced Light Microscopy

Coordinating lecturer

3748

Bachelor's thesis

Coordinating lecturer

3408

Biology of the Cell

Coordinating lecturer

3735

Heart & blood

Member of the teaching team

3354

Histology and Physiology of the Vertebrates

Member of the teaching team

3620

Immunity

Member of the teaching team

3951

Innovative techniques in imaging

Coordinating lecturer

3738

Lung and kidney

Member of the teaching team

3747

Multidisciplinary biomedical research

Member of the teaching team

Jelle HENDRIX

E-mail:

E-mail Jelle

Phone:

+3211269213

Location:

Campus Diepenbeek
Gebouw C
Office BMO-C002

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Prof. dr. Jelle HENDRIX

Membership

About Me

Research

Supervised PhDs

Phase separation as a hallmark for toxic protein conversion in tauopathies

Single-molecule fluorescence-based realtime structural biology of the adenosine A2A G-protein coupled receptor in microfabricated cells

Substrate-Dependent Conformational Landscape of Human DNA Ligases

Integrating coarse-grained molecular dynamics and fluorescence spectroscopy to unravel disordered protein condensates

Thermal-probing microdevices to unravel phase separating condensates involved in neurodegeneration

Development and application of a combined fluorescence microscopy and microfluidics tool for characterizing biomolecular condensates

Imaging strategies to investigate Glycine receptor splicing variant co-assembly and the impact on mobility and function

Investigation of the conformational dynamics of G protein-coupled receptors using single-molecule fluorescence microscopy

Nanoplasmonic sensing platform for lectin detection

Publications

Projects

Flanders BioImaging: Leading Imaging Application Integrated Service and Enablement (FBI-LIAISE) (Research)

MULTISCALE - The UHasselt MultiScale Optical Imaging Core: Infrastructure for nano- to centimeter length scale microscopy and analysis of 'big' 4D datasets (Research)

Structuromics@UHasselt - Experimental and theoretical platform for unravelling the spatiotemporal organisation of biomolecular assemblies (Research)

Integrating Coarse‐Grained Molecular Dynamics and Fluorescence Spectroscopy to Unravel Disordered Protein Condensates (Research)

Thermal-probing microdevices to unravel phase separating condensates involved in neurodegeneration (Research)

Thermal-probing microdevices to unravel phase separating condensates involved in neurodegeneration (Research)

Integrating Coarse‐Grained Molecular Dynamics and Fluorescence Spectroscopy to Unravel Disordered Protein Condensates (Research)

Beyond the biopsy: Innovative multimodal imaging to assess whole tumor heterogeneity in lung cancer (Research)

INSITE - A new combined experimental and theoretical framework for studying liquid protein condensates and its application to discover new targets for misfolded protein diseases (Research)

MULTISCALE - Infrastructure for nano- to centimeter length scale microscopy and big data analysis of optical imaging data (Research)

Protein folding/non-folding and dynamics (PROFOUND) (Research)

NATIVE - Single molecule optical microscopy and lipid nanotechnology 'ménage-à-deux' for deciphering multidrug transport in near-native environments (Research)

Substrate-Dependent Conformational Landscape of Human DNA Ligases (Research)

Single-molecule fluorescence-based realtime structural biology of the adenosine A2A G-protein coupled receptor in microfabricated cells (Research)

Single-molecule fluorescence-based realtime structural biology of the adenosine A2A G-protein coupled receptor in microfabricated cells (Research)

Substrate-Dependent Conformational Landscape of Human DNA Ligases (Research)

Unveiling molecular interactions through temperature-controlled microfluidic devices and fluorescence microscopy (Research)

Development of microdevices for screening membrane protein realtime structure in physiological conditions and investigation of multidrug resistance transporter LmrP (Research)

FABLITE – A light sheet microscopy and microfabrication 'ménage-àdeux' for real-time, high throughput and physiological structural biology. (Research)

Single-molecule structural investigations of tau protein (Research)

Marketable solution for advanced microscopy image correlation analysis. (Research)

Investigation of G-protein coupled receptors conformational dynamics via single-molecule fluorescence microscopy. (Research)

Single-molecule fluorescence-based realtime structural biology of the adenosine A2A G-protein coupled receptor in microfabricated cells (Research)

Substrate-Dependent Conformational Landscape of Human DNA Ligases (Research)

Development of microdevices for screening membrane protein realtime structure in physiological conditions and investigation of multidrug resistance transporter LmrP (Research)

FB-III ("FB triple-I") : Flanders BioImaging: Integrating Imaging Infrastructure from cell to man. (Research)

TRPV4 as a key driver of branch motility and somatic migration of microglial cells (Research)

Molecular dynamics and force generation: shedding new light on cell mechanosensing and communication (Research)

Development of microdevices for screening membrane protein realtime structure in physiological conditions and investigation of multidrug resistance transporter LmrP (Research)

Novel tools for dynamic structural biology (Research)

Biophotonics (Research)

Flanders BioImaging: towards an integrated, translational and multimodal imaging platform from molecule to man. (Research)

Single molecule Förster resonance energy transfer, and its application to ligand gated ion channel structure (Research)

Multipurpose multiphoton confocal laser scanning microscope (Research)

Patch-clamp fluorometry platform for unravelling the structure-function relationship of the GlyR (Research)

Education

Involved in the following courses

Academic year 2025 - 2026

Advanced Light Microscopy

Bachelor's thesis

Biology of the Cell

Heart & blood

Immunity

Innovative techniques in imaging

Lung and kidney

Multidisciplinary biomedical research

Academic year 2024 - 2025

Advanced Light Microscopy

Bachelor's thesis

Biology of the Cell

Heart & blood

Histology and Physiology of the Vertebrates

Immunity

Innovative techniques in imaging

Lung and kidney

Multidisciplinary biomedical research

Jelle HENDRIX

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