- head of the Dynamic Bioimaging Lab
- manager of the Advanced Optical Microscopy Centre
- researcher in the Biomedical Research Institute
- complete publication list on Pubmed
- scientific social network on Twitter and LinkedIN
Prof. dr. Jelle HENDRIX
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Prof. dr. Jelle HENDRIX
Associate Professor
Prof. dr. Jelle HENDRIX
About Me
Research
Discipline codes: Characterisation of biologically active (macro)molecules (01040402), Spectroscopic methods (01040107), Proteins (01060208), Molecular biophysics (03010402), Structural biology (03050304), Biophotonics (02070103), Analytical spectrometry (01040102), Intracellular compartments and transport (01060910), Soft condensed matter (01030410)
Supervised PhDs
Real-time live-cell structural biology of the glycine receptor
Veerle Lemmens for the title Doctor of Biomedical Sciences (doctorate in progress)
Supervised as Promotor
Development of microdevices for screening membrane protein realtime structure in physiological conditions and investigation of multidrug resistance transporter LmrP
Arnoud Jongeling for the title Doctor of Biomedical Sciences (doctorate in progress)
Supervised as Promotor
Phase separation as a hallmark for toxic protein conversion in tauopathies
Pedro Silva for the title Doctor of Biomedical Sciences (doctorate in progress)
Supervised as Promotor
Single-molecule fluorescence-based realtime structural biology of the adenosine A2A G-protein coupled receptor in microfabricated cells
Stijn Dilissen for the title Doctor of Biomedical Sciences (doctorate in progress)
Supervised as Promotor
Substrate-Dependent Conformational Landscape of Human DNA Ligases
Tom Kache for the title Doctor of Biomedical Sciences (doctorate in progress)
Supervised as Promotor
Integrating coarse-grained molecular dynamics and fluorescence spectroscopy to unravel disordered protein condensates
Eva Punter for the title Doctor of Biomedical Sciences (doctorate in progress)
Supervised as Promotor
Investigation of the conformational dynamics of G protein-coupled receptors using single-molecule fluorescence microscopy
Ivan Maslov for the title Doctor of Biomedical Sciences in 2023
Supervised as Promotor
Nanoplasmonic sensing platform for lectin detection
Alessia Pancaro for the title Doctor of Biomedical Sciences in 2023
Supervised as Promotor
Publications
JOURNAL CONTRIBUTION
Sub-millisecond conformational dynamics of the A(2A) adenosine receptor revealed by single-molecule FRET
Publish in 2023 in Communications Biology, Volume 6, Page's -
Authors
JOURNAL CONTRIBUTION
Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins
Publish in 2023 in NATURE METHODS, Volume 20, Page's 523 - 535
Authors
JOURNAL CONTRIBUTION
Particle-based phasor-FLIM-FRET resolves protein- protein interactions inside single viral particles
Publish in 2023 in BIOPHYSICAL REPORTS, Volume 3, Page's -
Authors
Projects
28 research projects have been found
Flanders BioImaging: Leading Imaging Application Integrated Service and Enablement (FBI-LIAISE) (Research)
01/01/2023 - 31/12/2026
MULTISCALE - The UHasselt MultiScale Optical Imaging Core: Infrastructure for nano- to centimeter length scale microscopy and analysis of 'big' 4D datasets (Research)
01/05/2022 - 30/04/2026
INSITE - A new combined experimental and theoretical framework for studying liquid protein condensates and its application to discover new targets for misfolded protein diseases (Research)
01/01/2024 - 31/12/2027
MULTISCALE - Infrastructure for nano- to centimeter length scale microscopy and big data analysis of optical imaging data (Research)
01/04/2022 - 31/03/2026
NATIVE - Single molecule optical microscopy and lipid nanotechnology 'ménage-à-deux' for deciphering multidrug transport in near-native environments (Research)
01/01/2022 - 31/12/2025
Single-molecule fluorescence-based realtime structural biology of the adenosine A2A G-protein coupled receptor in microfabricated cells (Research)
01/11/2023 - 31/10/2025
Single-molecule fluorescence-based realtime structural biology of the adenosine A2A G-protein coupled receptor in microfabricated cells (Research)
01/11/2021 - 31/10/2025
Unveiling molecular interactions through temperature-controlled microfluidic devices and fluorescence microscopy (Research)
01/10/2023 - 30/09/2025
Development of microdevices for screening membrane protein realtime structure in physiological conditions and investigation of multidrug resistance transporter LmrP (Research)
01/11/2021 - 31/10/2024
FABLITE – A light sheet microscopy and microfabrication 'ménage-àdeux' for real-time, high throughput and physiological structural biology. (Research)
01/10/2020 - 30/09/2024
Marketable solution for advanced microscopy image correlation analysis. (Research)
01/03/2022 - 31/12/2023
Investigation of G-protein coupled receptors conformational dynamics via single-molecule fluorescence microscopy. (Research)
01/09/2021 - 31/12/2023
Single-molecule fluorescence-based realtime structural biology of the adenosine A2A G-protein coupled receptor in microfabricated cells (Research)
01/11/2021 - 31/10/2023
Development of microdevices for screening membrane protein realtime structure in physiological conditions and investigation of multidrug resistance transporter LmrP (Research)
01/11/2019 - 31/10/2023
FB-III ("FB triple-I") : Flanders BioImaging: Integrating Imaging Infrastructure from cell to man. (Research)
01/02/2021 - 31/01/2023
TRPV4 as a key driver of branch motility and somatic migration of microglial cells (Research)
01/10/2019 - 30/09/2022
Molecular dynamics and force generation: shedding new light on cell mechanosensing and communication (Research)
01/10/2018 - 30/09/2022
Development of microdevices for screening membrane protein realtime structure in physiological conditions and investigation of multidrug resistance transporter LmrP (Research)
01/11/2019 - 31/10/2021
Flanders BioImaging: towards an integrated, translational and multimodal imaging platform from molecule to man. (Research)
01/02/2019 - 31/01/2021
Single molecule Förster resonance energy transfer, and its application to ligand gated ion channel structure (Research)
01/01/2018 - 31/12/2020
Education
Involved in the following courses
Academic year 2023 - 2024
Academic year 2023 - 2024
Academic year 2022 - 2023
Academic year 2022 - 2023
Jelle HENDRIX
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