We pave the way for novel designer drugs and screening assays by studying transient protein forms that are invisible to classical structural biology methods.
To do this, we uniquely specialise in analysing so-called fluorescence dynamics, the seemingly random fluorescence intensity fluctuations that occur when molecules (translationally) move, (rotationally) tumble or (structurally) wobble while being imaged.
Practically, we use super-sensitive commercial and home-built fluorescence microscopes, and study the structural and molecular function of proteins in cellular processes and disease. These proteins include cytoskeletal proteins, enzymes, ion channels, membrane receptors and condensating & aggregating proteins.
Feel free to take a look around on our website & contact us if you're interested in a collaboration, internship or employment.
Whether you're a student, doing a PhD or considering a postdoctoral career, if light microscopy intrigues you then our lab can help you to become an expert in Biophotonics! Contact us for an internship or job!
The Dynamic Bioimaging Lab is closely connected to UHasselt's core facility Advanced Optical Microscopy Centre. Visit the web site to discover: