Prof. dr. Niels HELLINGS
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Prof. dr. Niels HELLINGS
Full professor
Prof. dr. Niels HELLINGS
Membership
Research
Discipline codes: Autoimmunity (03021404), Autoimmunity (03061404), Autoimmunity (03011404)
Supervised PhDs
Influence of gammaherpesvirus infections on the development of multiple sclerosis
Annet van de Waterweg Berends for the title Doctor of Biomedical Sciences (doctorate in progress)
Supervised as Promotor
IL-13-overexpressing anti-inflammatory Mφs as a possible suppressor of premature immune aging after spinal cord injury
Naomi Veeningen for the title Doctor of Biomedical Sciences (doctorate in progress)
Supervised as Promotor
Exercise-induced Interleukin-15: a key myokine that improves immunological age by boosting autophagy
Lena Fonteyn for the title Doctor of Biomedical Sciences (doctorate in progress)
Supervised as Promotor
Adipose tissue-resident Th cells modulate the adipose tissue-brain axis in multiple sclerosis
Lisa Schuetz for the title Doctor of Biomedical Sciences (doctorate in progress)
Supervised as Copromotor
Evaluating the therapeutic potential of anti-CD6 monoclonal antibody therapy in inflammatory barrier diseases
Cynthia Gonzalez Muñoz for the title Doctor of Biomedical Sciences (doctorate in progress)
Supervised as Promotor
Thrilled by ticks to investigate protein Salp15 and it’s role in (auto)immune disease
Marie Sels for the title Doctor of Biomedical Sciences (doctorate in progress)
Supervised as Copromotor
Phosphodiesterase 4B and 4D inhibition: A sequential approach to unlock spinal cord injury repair
Femke Mussen for the title Doctor of Biomedical Sciences (doctorate in progress)
Supervised as Promotor
Associations between immunosenescence and cellular senescence as determinants of aging and pathology
Ana Ane Kouri for the title Doctor of Biomedical Sciences (doctorate in progress)
Supervised as Promotor
The therapeutic potential of irisin in MS: targeting three disease hallmarks with one compound
Marie Rutten for the title Doctor of Biomedical Sciences (doctorate in progress)
Supervised as Promotor
TIMPed wrapping of myelin in the PNS: unraveling the role of TIMP-1 in health and disease.
Femke Reubens for the title Doctor of Biomedical Sciences (doctorate in progress)
Supervised as Promotor
Novel vaccination and antiviral approaches for the prevention and treatment of COVID-19
Raúl Ramos Pupo for the title Doctor of Biomedical Sciences in 2026
Supervised as Copromotor
Privacy-Compliant Data Handling and Predictive Modelling in Multiple Sclerosis
Hamza Khan for the title Doctor of Biomedical Sciences in 2025
Supervised as Copromotor
Environmental regulation of immune cell balance: mechanistic insights and disease implications
Aleksandra Dyczko for the title Doctor of Biomedical Sciences in 2025
Supervised as Promotor
NEUTROPHILS: UNDERESTIMATED PLAYERS IN THE PATHOGENESIS OF MULTIPLE SCLEROSIS
Mirre De Bondt for the title Doctor of Biomedical Sciences in 2025
Supervised as Promotor
From barrier breach to brain invasion: Modulators of T cell migration in Multiple Sclerosis.
Gayel Duran for the title Doctor of Biomedical Sciences in 2024
Supervised as Copromotor
From Centralized to Federated: The journey of data in healthcare
Ashkan Pirmani for the title Doctor of Biomedical Sciences in 2024
Supervised as Copromotor
All you can EAAT3: restoring myelin, the brain's favourite fat.
Lieve van Veggel for the title Doctor of Biomedical Sciences in 2024
Supervised as Copromotor
Hugging it out: Targeting Oxytocin in Alzheimer’s Disease
Philippos Koulousakis for the title Doctor of Biomedical Sciences in 2024
Supervised as Copromotor
Picking the best isoform: PDE4D isoforms as therapeutic targets in Alzheimer's disease
Dean Paes for the title Doctor of Biomedical Sciences in 2023
Supervised as Copromotor
Endogenous modulators of CNS barriers in multiple sclerosis
Doryssa Hermans for the title Doctor of Biomedical Sciences in 2023
Supervised as Copromotor
Relieving the epigenetic blockade in progressive MS - making remyelination accessible again
Assia Tiane for the title Doctor of Biomedical Sciences in 2023
Supervised as Copromotor
PDE4 gene inhibition - a novel approach to treat demyelinating disorders
Melissa Schepers for the title Doctor of Biomedical Sciences in 2023
Supervised as Copromotor
When helpers go above and beyond: characterization of cytotoxic CD4+ T cells in multiple sclerosis
Cindy Hoeks for the title Doctor of Biomedical Sciences in 2023
Supervised as Promotor
Regulatory T cells in multiple sclerosis: good guys go bad at the gateway to the brain.
Paulien Baeten for the title Doctor of Biomedical Sciences in 2022
Supervised as Copromotor
OSM and TIMP-1 in multiple sclerosis: implications for neuroinflammation, remyelination, and neuroregeneration
Evelien Houben for the title Doctor of Biomedical Sciences in 2020
Supervised as Promotor
Umbilical cord stem cells as a candidate therapy for multiple sclerosis
Raf Donders for the title Doctor of Biomedical Sciences in 2019
Supervised as Promotor
Proteomic identification of novel players in autoimmune disease
Annelies Vanheel for the title Doctor of Biomedical Sciences in 2018
Supervised as Promotor
Functional PPV-based Conjugated Polymer Nanoparticles as a Versatile Bioimaging Probe.
Martijn Peters for the title Doctor of Sciences in 2017
Supervised as Copromotor
Cytomegalovirus and cytotoxic CD4+ T cells are key players in exacerbation of multiple sclerosis
Marjan Vanheusden for the title Doctor of Biomedical Sciences in 2017
Supervised as Copromotor
Lipoproteins in Multiple Sclerosis
Winde Jorissen for the title Doctor of Biomedical Sciences in 2017
Supervised as Copromotor
Evaluation of Multipotent Adult Progenitor Cells as a Candidate therapy for Multiple Sclerosis
Stylianos Ravanidis for the title Doctor of Biomedical Sciences in 2016
Supervised as Promotor
Fluorimetric imaging of nanoparticles in cells. Impact of nanoparticles on dendritic cells
Sarah Deville for the title Doctor of Biomedical Sciences in 2016
Supervised as Copromotor
Alterations in Circulating Follicular T cells in Multiple Sclerosis: Effect of treatment and genetic predisposition
Tessa Dhaeze for the title Doctor of Biomedical Sciences in 2015
Supervised as Copromotor
Gp130 cytokines in multiple sclerosis: a role in autoimmunity and remyelination
Kris Janssens for the title Doctor of Biomedical Sciences in 2015
Supervised as Promotor
Exploiting epigenetic mechanisms and dendritic cells to treat multiple sclerosis
Kristof Thewissen for the title Doctor of Biomedical Sciences in 2014
Supervised as Promotor
Neuroimmunological processes in rodent models of inflammation-associated depression
Steven Biesmans for the title Doctor of Biomedical Sciences in 2014
Supervised as Promotor
Interleukin-11 regulates myelin damage and repair
Anurag Maheshwari for the title Doctor of Biomedical Sciences in 2014
Supervised as Promotor
Cholesterol and its receptors in neuroinflammation
Silke Timmermans for the title Doctor of Biomedical Sciences in 2013
Supervised as Copromotor
Analyse van CD28null- cellen in auto-immuunziekten
Bieke Broux for the title Doctor of Biomedical Sciences in 2013
Supervised as Copromotor
Macrophages as mediators of protective autoimmunity in multiple sclerosis
Jeroen Bogie for the title Doctor of Biomedical Sciences in 2013
Supervised as Copromotor
The role of inhibitory neurotransmitters in CNS inflammation
Sofie Carmans for the title Doctor of Biomedical Sciences in 2011
Supervised as Promotor
The contribution of HLA-E restricted CD8+ T cells to the multiple sclerosis puzzle
Kim Pannemans for the title Doctor of Biomedical Sciences in 2010
Supervised as Copromotor
Defective myelination in mice lacking the lysophosphatidic acid receptor LPA1: newcomer models for demyelinating and neuroinflammatory diseases
Beatriz García Díaz for the title Doctor of Biomedical Sciences in 2010
Supervised as Promotor
The role of neurokines in neuroinflammation
Helena Slaets for the title Doctor of Biomedical Sciences in 2009
Supervised as Copromotor
Towards the integration of newly developed NMR techniques in the study of experimental autoimmune encephalomyelitis
Kurt Baeten for the title Doctor of Biomedical Sciences in 2009
Supervised as Copromotor
Study of CD4+CD25+FOXP3+ regulatory T cells in patients with multiple sclerosis
Koen Venken for the title Doctor of Biomedical Sciences in 2008
Supervised as Copromotor
Immune-mediated neuroprotection in mutliple sclerosis: Possible role for leukemia inhibitory factor
Joris Vanderlocht for the title Doctor of Biomedical Sciences in 2006
Supervised as Copromotor
Projects
102 research projects have been found
Timely wrapping of myelin in the PNS: unraveling the role of a new factor in health and disease (Research)
01/01/2025 - 31/12/2028
The therapeutic potential of irisin in MS: targeting three disease hallmarks with one compound (Research)
01/12/2024 - 30/11/2028
IL-34 mediates a novel non-canonical function of regulatory T cells by protecting brain barriers in neuroinflammation (Research)
01/11/2023 - 31/10/2027
Boosting cAMP using a sequential subtype-specific PDE4 inhibition approach: unlocking its potency and downstream signalling in spinal cord injurt (Research)
01/07/2025 - 30/06/2027
Supporting the oligodendrocyte-neuron coupling: pulling back to curtain on downstream PDE4D signalling (Research)
01/10/2023 - 30/09/2026
Associations between immunosenescence and cellular senescence as determinants of aging and pathology. (Research)
19/12/2023 - 31/05/2026
Cellular Senescence: an Underestimated Player in the Pathology of MS. (Research)
01/01/2024 - 31/12/2025
Using a novel pathway to timely wrap myelin in multiple sclerosis (Research)
01/10/2022 - 30/09/2025
Using a novel pathway to timely wrap myelin in multiple sclerosis (Research)
01/01/2023 - 30/06/2025
Evaluating the therapeutic potential of anti-CD6 monoclonal antibody therapy in inflammatory barrier diseases. (Research)
01/07/2022 - 30/06/2025
Train your defence system: muscle-derived myokines tackle immune aging by boosting autophagy (Research)
01/01/2021 - 31/12/2024
IL-13-overexpressing anti-inflammatory macrophages suppress trauma induced premature immune aging. (Research)
01/12/2020 - 30/11/2024
Neutrophils: underestimated players in the pathogenesis of multiple sclerosis (MS) (Research)
01/11/2022 - 31/10/2024
Epstein-Barr virus and multiple sclerosis risk: does imprinting of monocytes provide better explanations? (Research)
01/11/2022 - 31/10/2024
Epstein-Barr virus and multiple sclerosis risk: does imprinting of monocytes provide better explanations? (Research)
01/11/2020 - 31/10/2024
Neutrophils: underestimated players in the pathogenesis of multiple sclerosis (MS) (Research)
01/11/2020 - 31/10/2024
Inflammasome activation in TH lymphocytes, induced by mitochondrial impairment, causes local tissue damage in the brain of multiple sclerosis patients. (Research)
01/11/2020 - 31/10/2024
New kids on the block: Improving the care of people with multiple sclerosis by introducing "RADIOMICS" and "EPOMICS". (Research)
01/03/2020 - 29/02/2024
Deep immune-phenotyping of multiple sclerosis patients using advanced spectral flow cytometry (Research)
01/01/2022 - 31/12/2023
Identification of key molecules involved in the recruitment of pathogenic T cells into the inflamed MS brain (Research)
01/01/2020 - 31/12/2023
Structural funding institutions: structural funding for the operation of the Institute BIOMED (Research)
01/10/2012 - 31/12/2023
Adipose tissue-resident Th cells modulate the adipose tissue-brain axis in multiple sclerosis (Research)
01/11/2022 - 31/10/2023
Identification of key molecules involved in the recruitment of pathogenic T cells into the inflamed MS brain (Research)
01/10/2019 - 30/09/2023
Targeting phosphodiesterase 4D (PDE4D) isoforms, a novel approach to boost repair in multiple sclerosis (Research)
01/02/2021 - 31/05/2023
The epigenetic signature of myelin genes as innovative biomarker for progressive multiple sclerosis (Research)
01/01/2021 - 31/03/2023
Epstein Barr-virus and multiple sclerosis: new tricks from an old dog. Does imprinting of inflammatory monocytes provide an answer? (Research)
01/01/2020 - 31/12/2022
Structural funding institutions: project funding BIOMED for fundamental research (Research)
01/10/2012 - 31/12/2022
Epstein-Barr virus and multiple sclerosis risk: does imprinting of monocytes provide better explanations? (Research)
01/11/2020 - 31/10/2022
Neutrophils: underestimated players in the pathogenesis of multiple sclerosis (MS) (Research)
01/11/2020 - 31/10/2022
High performance decision support systems for multiple sclerosis treatment effectiveness in a real-world setting (Research)
01/10/2019 - 30/09/2022
Development of a Rapid Point of Care Device for Tuberculosis Diagnosis in Morocco (Education)
01/01/2018 - 31/08/2022
Protective versus damaging aspects of the immune reaction in relation to clinical outcome in the Limburg COVID-19 cohort (Research)
15/06/2020 - 14/06/2022
Restoring defective regulators: a step towards an autologous regulatory T cell-based therapy for multiple sclerosis (Research)
01/01/2020 - 31/03/2022
Oncostatin M limits inflammation and induces repair in the damaged CNS (Research)
01/01/2018 - 31/12/2021
Human and murine macrophages with a stable alternative activation as a therapeutic tool to promote neuroregeneration. (Research)
01/01/2018 - 31/12/2021
Fatty acid metabolism in control of the phenotype of foamy phagocytes in multiple sclerosis. (Research)
01/10/2018 - 30/09/2021
Oncostatin M-induced astrocytic TIMP-1: the key to central nervous system lesion repair. (Research)
01/10/2018 - 30/09/2021
Targeting enzymes on the splice variants level, a novel approach to boost repair in multiple sclerosis (Research)
01/09/2017 - 31/08/2021
Minimal Invasive Autopsy to Study Cause of Death, Contributing Conditions and Pathophysiology in Deceased COVID-19 patients (Research)
22/05/2020 - 21/05/2021
Targeting enzymes on the splice variants level, a novel approach to boost repair in multiple sclerosis (Research)
01/02/2019 - 31/01/2021
The epigenetic signature of myelin genes as innovative biomarker for progressive multiple sclerosis (Research)
01/01/2019 - 31/12/2020
Unraveling the hidden pathways of inhaled combustion-derived particles from air pollution (Research)
01/10/2018 - 09/11/2020
Neutrophils: underestimated players in the pathogenesis of multiple sclerosis (MS) (Research)
01/11/2020 - 01/11/2020
Relieving the epigenetic blockade in progressive multiple sclerosis – making repair possible again (Research)
17/01/2019 - 31/12/2019
Smart nanoparticles for bioimaging disease activity in progressive Multiple sclerosis (Research)
01/01/2018 - 31/12/2019
Interaction of regulatory T cells with cells of the central nervous system in multiple sclerosis (Research)
01/01/2018 - 31/12/2019
Towards personalized medicine: predicting disease progression of MS patients from trajectory data (Research)
15/06/2019 - 31/08/2019
Oncostatin M-induced astrocytic TIMP-1: the key to central nervous system lesion repair (Research)
01/10/2016 - 30/09/2018
Fatty acid metabolism in control of the phenotype of phagocytes in MS lesions (Research)
01/10/2015 - 30/09/2018
Cholesterol receptors and transporters as crucial regulators of CNS inflammation (Research)
01/01/2012 - 31/08/2018
What is responsible antibiotic use? A search for a global definition, associated measures, its barriers and ethical aspects. (Research)
01/08/2017 - 31/07/2018
Skeletal muscle bioenergetics in multiple sclerosis: disease- or inactivity- induced impairments? (Research)
01/10/2017 - 16/01/2018
Development collaboration with Scandinavian partner universities (Education)
01/01/2017 - 31/12/2017
Oncostatin M as a master regulator of central nervous system lesion repair (Research)
01/10/2015 - 30/09/2016
Ephrins and their receptors are crucial for the recruitment of pathogenic TH17 cells to the central nervous system in multiple sclerosis patients (Research)
01/10/2013 - 30/09/2016
Multipotent Adult Progenitor Cells as potential modulators of Multiple Sclerosis (Research)
01/01/2015 - 30/04/2016
BOF NI project: A role for expanded CD4+CD28null T cells in patients with multiple sclerosis? (Research)
01/01/2012 - 31/12/2015
FWO research project: A role for expanded CD4+CD28null T cells in patients with multiple sclerosis? (Research)
01/01/2012 - 31/12/2015
The multiple faces of microglia in brain diseases. Phenotyping microglia in the acute-chronic switch of autoimmune, traumatic and excitability disorders (Research)
01/01/2011 - 31/12/2015
FWO travel grant to Bieke Broux for a long stay at the University of Montreal under her postdoctoral research (Research)
13/09/2013 - 12/09/2015
Oncostatin M as a master regulator of central nervous system lesion pathology (Research)
01/01/2011 - 31/12/2014
Design and Synthesis of Multifunctional PPV-Based Nanoparticles for Multiple Sclerosis Research (Research)
01/10/2013 - 30/12/2014
Plant sterols: potent inducers of remyelination in Multiple Sclerosis? (Research)
01/10/2013 - 30/09/2014
A pathogenic role for cytotoxic CD4+CD28null T-cells in multiple sclerosis? (Research)
01/01/2012 - 31/12/2013
Therapeutic application of multipotent stem cells in an animal model of multiple sclerosis (Research)
01/01/2010 - 31/12/2013
Dendritic cells as mediators of regulatory T-cell processes in multiple sclerosis (Research)
01/01/2010 - 31/12/2013
Protective effects of neuropoietic cytokines on pathological CNS responses in multiple sclerosis (Research)
01/01/2010 - 31/12/2013
Can non-invasive brain stimulation enhance neuroplasticity mediated by brain-derived neurotrophic factor (BDNF) in the healthy and injured brain: a new therapeutic tool for improving recovery after stroke? (Research)
01/01/2010 - 31/12/2013
The role of liver x receptors in the macrophage response after myelin phagocytosis (Research)
01/10/2009 - 30/09/2013
SialoTarg: Advanced vaccines and pharmaceuticals targeted to macrophages via sialoadhesin (Research)
01/03/2009 - 28/02/2013
Improving functional recovery after spinal cord injury by a combined application of antiinflammatory interleukins and neural stem cells (Research)
01/01/2009 - 31/12/2012
IWT grant: Macrophages as mediators of protectieve auto-immunity. (Research)
01/01/2009 - 31/12/2012
Clinical and preclinical research of the effect of cellular mediators on the modulation of pathogenic responses in multiple sclerosis (Research)
01/01/2009 - 31/12/2012
Education
Involved in the following courses
Academic year 2026 - 2027
Academic year 2026 - 2027
Academic year 2025 - 2026
Academic year 2025 - 2026
Niels HELLINGS
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