Expertise
The Advanced Optical Microscopy Centre can help design, execute and troubleshoot your imaging experiments. Our team has theoretical and practical expertise in a broad selection of imaging methods and applications ranging from image correlation methods over super-resolution microscopy to functional live-tissue imaging. Our consultation services are open to everyone.
Publications
The AOMC Publications spreadsheet lists (almost) all of the recent publications that made use of AOMC equipment.
Expertise
Live and fixed samples
At the AOMC, all microscopes are capable of imaging both live and fixed samples. However, each system (technique) has its own set of advantages and disadvantages, making them more or less suited for different applications. Every microscope is equipped with an enclosing incubator and stage inserts that allow precise temperature and pH control for optimal sample conditions.
Superresolution microscopy
The diffraction-limited nature of light microscopy does not always provide sufficient resolution to see all desired details. At the AOMC, multiple techniques are available to record images with improved (super) resolution. Each of these methods has its own set of advantages and disadvantages, so they can be matched to almost any research question.
Label-free imaging
It is not always required to label a sample with fluorophores in order to visualize it. Several structures and components can be imaged using label-free imaging techniques.
Diffusion and Binding
Biomolecules hide a wealth of information in the way they move about! We specialize in fluctuation spectroscopy methods for quantifying biomolecular diffusion and binding processes.
Conformation
Biomolecules hide a wealth of information in the way they move about! We specialize in single-molecule methods for quantifying biomolecular structure and conformational dynamics.
Time-resolved fluorescence
Fluorophores hide a wealth of information in the way they fluoresce! We specialize in time-resolved methods for quantifying fluorescence lifetimes and anisotropy.